[Captopril and enalapril in the treatment of renal hypertension].

Abstract

Captopril and Enalapril, angiotensin converting enzyme inhibitors, were used in the treatment of grave renal hypertension. The treatment concerned 40 randomly selected patients with the average creatinine clearance of 55.7 ml/min. The patients were divided in two groups: the first groups was ril. The good regulation of blood pressure was achieved only in combination with furosemide and protreated with captopril and the second with enalappranolol. Furosemide was given to all patients, and propranolol to all treated with captopril and to 12 subjects treated with enalapril. The angiotensin converting enzyme increased plasma renine activity and decreased aldosterone concentration in the serum. No change in renal function was noted. Proteinuria was decreased. Side-effects were manifest in two patients only treated with captopril. In conclusion it can be said that angiotensin converting enzyme inhibitors are efficient in the treatment of renal hypertension.

• Authors: H Hasanagić, Lj Djukanović, Z Subotić, V Nesić, G Cavrić
• Journal: Srpski arhiv za celokupno lekarstvo (Srp Arh Celok Lek) 1990 Jul-Aug Vol. 118 Issue 7-8 Pg. 285-90 ISSN: 0370-8179 [Print] Serbia
• Vernacular Title: Kaptopril i enalapril u lecenju renalne hipertenzije.
• PMID: 2097777 (Publication Type: Clinical Trial, Controlled Clinical Trial, English Abstract, Journal Article)

Chemical References

• Enalapril
• Captopril

Topics

• Blood Pressure (drug effects)
• Captopril (adverse effects, therapeutic use)
• Enalapril (adverse effects, therapeutic use)
• Humans
• Hypertension, Renal (drug therapy, physiopathology)
• Middle Aged