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Epithelioid hemangioendothelioma presenting as a vertebral fracture.

Abstract
Epithelioid hemagioendothelioma (EH) is a rare vascular tumor with an intermediate biological behavior between hemangioma and angiosarcoma. Vertebral location is even more rare, and because the number of reported cases of EH is small and the follow-up periods short, the best surgical treatment, the role of radiotherapy and chemotherapy, as well as the definitive prognosis are still not established. The authors report a case of EH which presented as a vertebral fracture with neurological impairment, where a percutaneous biopsy was inconclusive. Treatment included vertebrectomy, with complete excision of the lesion, spinal canal decompression and vertebral stabilization. Anatomopathological study revealed an epithelioid vascular neoplasm with low mitotic index, and tumor cells reactive to vimentin, CD31 and CD34, leading to the diagnosis of Grade I Epithelioid Hemangioendothelioma. Because of the wide resection achieved and the low aggressiveness of the lesion, no adjuvant radio or chemotherapy was undertaken, and at 6 years follow-up there are no signs of recurrence or metastasis.
AuthorsNuno Neves, Francisco Lima-Rodrigues, Manuel Ribeiro-Silva, Pedro Cacho-Rodrigues, Catarina Eloy, Maria Emília Paiva, Rui Pinto
JournalActa reumatológica portuguesa (Acta Reumatol Port) 2010 Jul-Sep Vol. 35 Issue 3 Pg. 370-4 ISSN: 0303-464X [Print] Portugal
PMID20975643 (Publication Type: Case Reports, Journal Article)
Topics
  • Female
  • Hemangioendothelioma, Epithelioid (complications)
  • Humans
  • Lumbar Vertebrae (injuries)
  • Middle Aged
  • Spinal Fractures (etiology)

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