Abstract |
Methylergonovine (MEV) is a semi-synthetic ergot alkaloid used in the prevention and control of postpartum hemorrhage. This report describes 12 newborns born on the same day in a local country hospital in Turkey and developed sepsis-like symptoms and encephalopathy within the first 6 h of life due to accidental administration of MEV instead of vitamin K in the delivery room. The major features of MEV poisoning were lethargy (41.7%), seizure (75.0%), feeding intolerance (66.6%), hypoventilation (58.3%), irritability (25%), and peripheral circulatory abnormalities (58.3%). As a conclusion, clinical findings of ergot toxicity in newborns cannot be distinguished from infectious disease or neonatal encephalopathy.
|
Authors | Ahmet Yagmur Bas, Nihal Demirel, Ahmet Soysal, Kahraman Arslan, Ugur Dilmen |
Journal | European journal of pediatrics
(Eur J Pediatr)
Vol. 170
Issue 5
Pg. 633-7
(May 2011)
ISSN: 1432-1076 [Electronic] Germany |
PMID | 20972685
(Publication Type: Journal Article)
|
Chemical References |
|
Topics |
- Diagnosis, Differential
- Ergotism
(diagnosis)
- Female
- Humans
- Infant, Newborn
- Male
- Medication Errors
- Methylergonovine
(poisoning, therapeutic use)
- Sepsis
(diagnosis)
|