Abstract | IMPORTANCE OF THE FIELD: AREAS COVERED IN THIS REVIEW: Various prodrug strategies evaluated for cytarabine are discussed. Then, the review summarizes the drug delivery systems that have been used for more effective cancer therapy. WHAT THE READER WILL GAIN: This review provides in-depth discussion of the prodrug strategy and delivery systems of cytarabine derivatives for the treatment of cancer. The design of cytarabine prodrugs and delivery systems provides insights for designing the next generation of more effective anticancer agents with enhanced delivery and stability. TAKE HOME MESSAGE:
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Authors | Bhupender S Chhikara, Keykavous Parang |
Journal | Expert opinion on drug delivery
(Expert Opin Drug Deliv)
Vol. 7
Issue 12
Pg. 1399-414
(Dec 2010)
ISSN: 1744-7593 [Electronic] England |
PMID | 20964588
(Publication Type: Journal Article, Review)
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Chemical References |
- Antineoplastic Agents
- Prodrugs
- Cytarabine
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Topics |
- Antineoplastic Agents
(administration & dosage, therapeutic use)
- Cytarabine
(administration & dosage, therapeutic use)
- Drug Delivery Systems
- Humans
- Leukemia
(drug therapy)
- Lymphoma, Non-Hodgkin
(drug therapy)
- Prodrugs
(administration & dosage, therapeutic use)
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