Abstract | OBJECTIVE: The purpose of this study was to investigate the efficacy and tolerance of an additional phosphate enema prior to non- laxative CT colonography (CTC). METHODS: 71 patients (mean age 80 years, 28 male, 43 female) underwent non- laxative CTC following 4 oral doses of diluted 2% w/w barium sulphate. Patients were invited to self-administer a phosphate enema 2 h before CTC. An experienced observer graded the volume of retained stool (1 (nil) to 4 (>75% bowel circumference coated)), retained fluid ((1 (nil) to 4 (>50% circumference obscured)), retained stool tagging quality (1 (untagged) to 5 (≥75% to 100%) tagged) and confidence a polyp ≥6 mm could be excluded (yes/no) for each of six colonic segments. Tolerance of the enema was assessed via questionnaire. Data were analysed between those using and not using the enema by Mann-Whitney and Fisher's exact test. 18/71 patients declined the enema. RESULTS: There was no reduction in residual stool volume with enema use compared with non-use either overall (mean score 2.6 vs 2.7, p = 0.76) or in the left colon (mean 2.3 vs 2.4, p = 0.47). Overall tagging quality was no different (mean score 4.4 vs 4.3, p = 0.43). There was significantly more retained left colonic fluid post enema (mean score 1.9 vs 1.1, p<0.0001), and diagnostic confidence in excluding polyps was significantly reduced (exclusion not possible in 35% segments vs 21% without enema, p = 0.006). Of 53 patients, 30 (56%) found the enema straightforward to use, but 4 (8%) found it unpleasant. CONCLUSION:
Phosphate enema use prior to non- laxative CTC leads to greater retained fluid, reducing diagnostic confidence, and is not recommended.
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Authors | W Davis, P Nisbet, C Hare, P Cooke, S A Taylor |
Journal | The British journal of radiology
(Br J Radiol)
Vol. 84
Issue 998
Pg. 120-5
(Feb 2011)
ISSN: 1748-880X [Electronic] England |
PMID | 20959374
(Publication Type: Journal Article)
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Chemical References |
- Cathartics
- Contrast Media
- Barium Sulfate
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Topics |
- Aged
- Aged, 80 and over
- Barium Sulfate
- Cathartics
(administration & dosage)
- Colonography, Computed Tomographic
(methods)
- Contrast Media
- Enema
(adverse effects, methods)
- Feces
- Female
- Humans
- Male
- Patient Satisfaction
- Surveys and Questionnaires
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