Definite and probable septic pericarditis in hemodialysis.

Although the incidence of septic pericarditis in hemodialysis populations is less frequent in the modern antibiotic era, it is still a cause of death partly because diagnosis is sometimes difficult and uncertain.
From 2002 to 2006, 12 out of a total of 12,213 maintenance hemodialysis patients were referred for management of septic pericarditis. Patients were diagnosed as either definite or probable septic pericarditis. A definite diagnosis of septic pericarditis is based on the discovery of pathogenic bacteria in pericardial effusion, whereas a probable diagnosis is based on the proof of bacterial infection elsewhere in a patient with otherwise unexplained pericarditis, or appropriate response to a trial of systemic antibiotics.
Four (33.3%) patients were diagnosed as definite pericarditis, whereas eight (66.7%) patients as probable pericarditis. It was found that although oxacillin-resistant Staphylococcus aureus (ORSA) (4/12 or 33.3%) and tuberculous (4/12 or 33.3%) pericarditis were common, salmonella pericarditis (2/12 or 16.7%) was also not uncommon. Pericardiocentesis, or pericardial window with pericardiectomy, was performed in three (25%) and two (16%) of patients with cardiac tamponade, respectively. Two patients died because of severe ORSA (1/12 or 8%) and salmonella (1/12 or 8%) sepsis. Finally, there were four (33%) patients who developed constrictive pericarditis after follow-up.
These data are important because the spectrum of septic pericarditis was clearly different between Taiwan and other developed countries. Furthermore, it is the only report in which patients were diagnosed as either definite or probable septic pericarditis, therefore improving the sensitivity of diagnosis as in the case of tuberculous pericarditis.
AuthorsJing-Ren Tseng, Ming-Jse Lee, Ja-Liang Lin, Tzung-Hai Yen
JournalRenal failure (Ren Fail) Vol. 32 Issue 10 Pg. 1177-82 ( 2010) ISSN: 1525-6049 [Electronic] England
PMID20954978 (Publication Type: Journal Article)
  • Aged
  • Aged, 80 and over
  • Female
  • Humans
  • Kidney Failure, Chronic (epidemiology)
  • Male
  • Middle Aged
  • Pericardial Effusion (radiography)
  • Pericardiocentesis
  • Pericarditis (diagnosis, epidemiology, microbiology, surgery)
  • Renal Dialysis
  • Sepsis (diagnosis, epidemiology)
  • Tomography, X-Ray Computed

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