Abstract |
Through two prospective studies, we evaluated the use of polyester ( Mersilene) sutures in penetrating keratoplasty. Study 1 was a randomized comparison of combined running and interrupted Mersilene and nylon sutures (n = 45). Study 2 was a case series of single running Mersilene with postoperative adjustment of suture tension to manage astigmatism (n = 23). Study 1 demonstrated that Mersilene interrupted sutures were 5.5 times more likely to have handling-related complications compared to nylon (P = 0.01); in addition, they were 3 times as likely to have tissue-related complications as nylon interrupted sutures (P = 0.16). Study 2 demonstrated a complication rate of 69% when Mersilene was used as a single adjustable running suture. At 6 months postoperatively, the median refractive astigmatism for the adjustable cases was 3.37 D (mean, 4.03 +/- 2.37 D). Eyes in Study 2 with significant suture-related complications were 2.85 times more likely to have greater than 4 D of refractive astigmatism than were eyes without suture-related complications. We concluded that Mersilene is an undesirable suture for use in penetrating keratoplasty.
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Authors | B A Bertram, C Drews, M Gemmill, J Guell, M Murad, G O Waring |
Journal | Transactions of the American Ophthalmological Society
(Trans Am Ophthalmol Soc)
Vol. 88
Pg. 237-49; discussion 249-54
( 1990)
ISSN: 0065-9533 [Print] United States |
PMID | 2095023
(Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.)
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Chemical References |
- Nylons
- Phthalic Acids
- Polyethylene Terephthalates
- Lavsan
- Polyethylene Glycols
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Topics |
- Adult
- Aged
- Astigmatism
(surgery)
- Corneal Diseases
(etiology)
- Evaluation Studies as Topic
- Female
- Humans
- Intraoperative Complications
- Keratoplasty, Penetrating
- Male
- Middle Aged
- Nylons
- Phthalic Acids
(adverse effects)
- Polyethylene Glycols
(adverse effects)
- Polyethylene Terephthalates
- Prospective Studies
- Suture Techniques
- Sutures
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