HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Inadequacy of a polyester (Mersilene) suture for the reduction of astigmatism after penetrating keratoplasty.

Abstract
Through two prospective studies, we evaluated the use of polyester (Mersilene) sutures in penetrating keratoplasty. Study 1 was a randomized comparison of combined running and interrupted Mersilene and nylon sutures (n = 45). Study 2 was a case series of single running Mersilene with postoperative adjustment of suture tension to manage astigmatism (n = 23). Study 1 demonstrated that Mersilene interrupted sutures were 5.5 times more likely to have handling-related complications compared to nylon (P = 0.01); in addition, they were 3 times as likely to have tissue-related complications as nylon interrupted sutures (P = 0.16). Study 2 demonstrated a complication rate of 69% when Mersilene was used as a single adjustable running suture. At 6 months postoperatively, the median refractive astigmatism for the adjustable cases was 3.37 D (mean, 4.03 +/- 2.37 D). Eyes in Study 2 with significant suture-related complications were 2.85 times more likely to have greater than 4 D of refractive astigmatism than were eyes without suture-related complications. We concluded that Mersilene is an undesirable suture for use in penetrating keratoplasty.
AuthorsB A Bertram, C Drews, M Gemmill, J Guell, M Murad, G O Waring
JournalTransactions of the American Ophthalmological Society (Trans Am Ophthalmol Soc) Vol. 88 Pg. 237-49; discussion 249-54 ( 1990) ISSN: 0065-9533 [Print] United States
PMID2095023 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.)
Chemical References
  • Nylons
  • Phthalic Acids
  • Polyethylene Terephthalates
  • Lavsan
  • Polyethylene Glycols
Topics
  • Adult
  • Aged
  • Astigmatism (surgery)
  • Corneal Diseases (etiology)
  • Evaluation Studies as Topic
  • Female
  • Humans
  • Intraoperative Complications
  • Keratoplasty, Penetrating
  • Male
  • Middle Aged
  • Nylons
  • Phthalic Acids (adverse effects)
  • Polyethylene Glycols (adverse effects)
  • Polyethylene Terephthalates
  • Prospective Studies
  • Suture Techniques
  • Sutures

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: