[A case of recurrent high-grade endometrial stromal sarcoma controlled by a combination of Ifosfamide, adriamycin, and cisplatin].

Abstract

A 52-year-old woman with recurrent high-grade endometrial stromal sarcoma presented with left hypochondralgia. She had undergone total hysterectomy and bilateral salpingo-oophorectomy for the disease over the past six months, and preferred not to receive additional treatment. The following regimen of chemotherapy was given: each course consisted of ifosfamide (1,000 mg/m²) on days 1-5, adriamycin (60 mg/m²) on day 1, and cisplatin (15 mg/m²) on days 1-5. After 4 courses of the chemotherapy, the intraabdominal mass and multiple pulmonary nodules were reduced 45. 1% from the beginning. This case suggests that IAP might be effective chemotherapy for patients with high-grade endometrial stromal sarcoma.

• Authors: Michiyo Ushijima, Yoshihiro Yamakawa, Eriko Sakabe, Hiroki Waki, Kiyoshi Katou
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 37 Issue 10 Pg. 2003-5 (Oct 2010) ISSN: 0385-0684 [Print] Japan
• PMID: 20948274 (Publication Type: Case Reports, Journal Article)

Chemical References

• Doxorubicin
• Cisplatin
• Ifosfamide

Topics

• Abdominal Neoplasms (diagnostic imaging, drug therapy, secondary)
• Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
• Cisplatin (administration & dosage, therapeutic use)
• Doxorubicin (administration & dosage, therapeutic use)
• Endometrial Neoplasms (diagnostic imaging, drug therapy, pathology, surgery)
• Female
• Humans
• Ifosfamide (administration & dosage, therapeutic use)
• Lung Neoplasms (diagnostic imaging, drug therapy, secondary)
• Middle Aged
• Recurrence
• Sarcoma, Endometrial Stromal (diagnostic imaging, drug therapy, pathology, surgery)
• Tomography, X-Ray Computed