HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

[Granulocytic sarcoma of the prostate].

Abstract
A 71-year-old man with dysuria was referred to our hospital. The level of serum prostate specific antigen was slightly elevated (4.66 ng/ml), and digital rectal examination revealed a stony hard prostate mass. We performed a transrectal prostate biopsy because malignancy was suspected. Histological examination revealed leukemia-like cells, and bone-marrow examination (aspiration) was performed to determine the location of the original lesion. However, no leukemia-like cells or any other form of malignant cells were identified. Clinical imaging confirmed the absence of any other lesions, and granulocytic sarcoma of the prostate was subsequently diagnosed. We treated the cancer with radiotherapy at a dose of 40 Gy and dysuria improved. Furthermore, significant reduction in prostate volume was confirmed. Four months after initial presentation, the patient developed acute myeloid leukemia [M2 by French-American-British classification]. Induction chemotherapy was initiated, and the patient was successfully induced to complete remission. Twenty months later, the patient showed relapse. Despite salvage chemotherapy, he died of brain hemorrhage twenty-four months after complete remission.
AuthorsMasahiro Nitta, Akio Hoshi, Tetsuo Shinozaki, Syuichi Soeda, Masayoshi Kawakami, Hakushi Kin, Nobuyuki Nakajima, Kazuya Hanai, Seiichi Kato, Takeshi Nomoto, Yukio Usui, Toshiro Terachi
JournalHinyokika kiyo. Acta urologica Japonica (Hinyokika Kiyo) Vol. 56 Issue 9 Pg. 521-5 (Sep 2010) ISSN: 0018-1994 [Print] Japan
PMID20940529 (Publication Type: Case Reports, English Abstract, Journal Article)
Topics
  • Aged
  • Humans
  • Leukemia, Myeloid, Acute (etiology)
  • Male
  • Prostatic Neoplasms (pathology)
  • Sarcoma, Myeloid (pathology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: