Primary amelanotic melanoma of the cervix: case report with review of literature.

Abstract

Primary malignant melanoma of the uterine cervix is a rare neoplasm with poor prognosis. It may be misdiagnosed especially when amelanotic, in which case immunohistochemistry is useful in reaching the diagnosis. We present one such case of a 65-year-old postmenopausal female patient presenting with bleeding per vaginum. Speculum examination revealed an ulcero-proliferative growth involving the cervix. On histopathological examination it was originally suspected to be a poorly differentiated carcinoma or a non-epithelial malignant tumor, but was subsequently correctly diagnosed by immunohistochemical staining with the HMB-45 antibody and S-100 protein.

• Authors: Rajan Duggal, Radhika Srinivasan
• Journal: Journal of gynecologic oncology (J Gynecol Oncol) Vol. 21 Issue 3 Pg. 199-202 (Sep 2010) ISSN: 2005-0399 [Electronic] Korea (South)
• PMID: 20922145 (Publication Type: Journal Article)