[Therapy of penile viral condylomata with 0.5% podophyllotoxin].

Abstract

Twenty male patients with penile warts (HPV induced papular and flat condylomata) attending the Venereal Disease Clinic at the Department of Dermatology, University di Pavia were treated with podophyllotoxin 0.5% in ethanol, self applied twice daily for 3 consecutive days, followed by 4 days without treatment. All the patients were cured after a maximum of 6 treatments; 10 patients (50%) were cured after 1 or 2 treatments. Three patients did not attend regularly at the control visits; 17 patients completed the study. Eight of the 17 patients (47.1%) showed recurrences of the warts; all of them were cured after successive podophyllotoxin treatments. Tolerance was good and only a few patients (30%) had mild adverse reactions. In conclusion podophyllotoxin 0.5% appeared to be safe and effective for the self treatment of genital warts.

• Authors: G Caresana, C Del Forno
• Journal: Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia (G Ital Dermatol Venereol) Vol. 125 Issue 12 Pg. LXV-LXVIII (Dec 1990) ISSN: 0392-0488 [Print] Italy
• Vernacular Title: Terapia di condilomi virali penieni con podofillotossina allo 0.5%.
• PMID: 2091977 (Publication Type: Clinical Trial, English Abstract, Journal Article)

Chemical References

• Podophyllotoxin

Topics

• Adolescent
• Adult
• Condylomata Acuminata (drug therapy)
• Follow-Up Studies
• Humans
• Male
• Penile Neoplasms (drug therapy)
• Podophyllotoxin (administration & dosage, therapeutic use)
• Time Factors