Abstract |
To study the effect of nimodipine on the outcome of head injury, three hundred and fifty-two patients who were not obeying commands were randomised to placebo or nimodipine (2 mg per hour intravenously for 7 days). The 2 groups were well matched for important prognostic features. Six months after injury, more of the patients who were given nimodipine had a favourable outcome (moderate/good recovery) than in the control group, but the increase in favourable outcome (8%) was not significant statistically.
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Authors | G Teasdale, I Bailey, A Bell, J Gray, R Gullan, U Heiskanan, P V Marks, H Marsh, A D Mendelow, G Murray |
Journal | Acta neurochirurgica. Supplementum
(Acta Neurochir Suppl (Wien))
Vol. 51
Pg. 315-6
( 1990)
Austria |
PMID | 2089926
(Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
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Chemical References |
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Topics |
- Craniocerebral Trauma
(drug therapy, mortality, physiopathology)
- Humans
- Nimodipine
(therapeutic use)
- Prognosis
- Prospective Studies
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