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The effect of nimodipine on outcome after head injury: a prospective randomised control trial. The British/Finnish Co-operative Head Injury Trial Group.

Abstract
To study the effect of nimodipine on the outcome of head injury, three hundred and fifty-two patients who were not obeying commands were randomised to placebo or nimodipine (2 mg per hour intravenously for 7 days). The 2 groups were well matched for important prognostic features. Six months after injury, more of the patients who were given nimodipine had a favourable outcome (moderate/good recovery) than in the control group, but the increase in favourable outcome (8%) was not significant statistically.
AuthorsG Teasdale, I Bailey, A Bell, J Gray, R Gullan, U Heiskanan, P V Marks, H Marsh, A D Mendelow, G Murray
JournalActa neurochirurgica. Supplementum (Acta Neurochir Suppl (Wien)) Vol. 51 Pg. 315-6 ( 1990) Austria
PMID2089926 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
Chemical References
  • Nimodipine
Topics
  • Craniocerebral Trauma (drug therapy, mortality, physiopathology)
  • Humans
  • Nimodipine (therapeutic use)
  • Prognosis
  • Prospective Studies

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