[Clinical immunological rationale of interferon therapy in chronic bacterial prostatitis].

Abstract

The study of changes in the immune status of patients with chronic bacterial prostatitis demonstrated changes in immunological parameters reflecting depression of the immune system (subnormal levels of interferon alpha, gamma, sIgA, functional activity of neutrophils, high concentration of IgA, IgG, IgM). Thus, combined treatment of chronic bacterial prostatitis must include administration of immunomodulators.

• Authors: A A Kamalov, E A Efremov, S D Dorofeev, A A Tret'iakov, D A Okhobotov, Ia I Mel'nik, D A Bedretdinova
• Journal: Urologiia (Moscow, Russia : 1999) (Urologiia) 2010 Jan-Feb Issue 1 Pg. 34-8 ISSN: 1728-2985 [Print] Russia (Federation)
• PMID: 20886729 (Publication Type: Journal Article, Randomized Controlled Trial)

Chemical References

• Anti-Bacterial Agents
• Immunologic Factors
• Interferon-alpha
• Interferon-gamma

Topics

• Adult
• Anti-Bacterial Agents (administration & dosage, therapeutic use)
• Double-Blind Method
• Drug Therapy, Combination
• Humans
• Immunologic Factors (administration & dosage, blood, therapeutic use)
• Interferon-alpha (administration & dosage, blood, therapeutic use)
• Interferon-gamma (blood)
• Leukocyte Count
• Male
• Middle Aged
• Prostate (drug effects, immunology, metabolism, microbiology)
• Prostatitis (diagnosis, drug therapy, immunology, microbiology)
• Severity of Illness Index
• Treatment Outcome
• Young Adult