The usefulness of toluidine red unheated serum test in the diagnosis of HIV-negative neurosyphilis.

Abstract

We retrospectively analyzed the Venereal Disease Research Laboratory test, Treponema pallidum particle agglutination test, and toluidine red unheated serum test (TRUST) in 41 cases of HIV-negative neurosyphilis and 34 non-neurologic syphilitic patient and found that serum-TRUST titers could be the indication of lumbar puncture in syphilitic patients and a reactive cerebrospinal fluid-TRUST is considered diagnostic to neurosyphilis.

• Authors: Ying Jiang, Xiaohong Chen, Xiaomeng Ma, Yu Yang, Fuhua Peng, Xueqiang Hu
• Journal: Sexually transmitted diseases (Sex Transm Dis) Vol. 38 Issue 3 Pg. 244-5 (Mar 2011) ISSN: 1537-4521 [Electronic] United States
• PMID: 20871491 (Publication Type: Journal Article)

Chemical References

• Antibodies, Bacterial
• Azo Compounds
• Reagins
• toluidine red

Topics

• Agglutination Tests (methods)
• Antibodies, Bacterial (blood, cerebrospinal fluid)
• Azo Compounds
• Chi-Square Distribution
• Humans
• Leukocyte Count
• Neurosyphilis (diagnosis, microbiology)
• Reagins (blood, cerebrospinal fluid)
• Retrospective Studies
• Sensitivity and Specificity
• Syphilis Serodiagnosis (methods)
• Treponema pallidum (isolation & purification)