Abstract | BACKGROUND:
Biomarkers are good potential tools for early cancer diagnosis. Here we have analyzed eight different pteridines in the urine samples of cancer patients and compared them with samples from healthy subjects. Pteridines are important cofactors in the process of cell metabolism, and they have recently become a focal point of cancer screening research because certain pteridine levels have been shown to reflect the presence of cancers. METHODS: RESULTS: CONCLUSION: Some pteridine levels can be used as biomarkers for noninvasive diagnosis of cancer; however, more data is needed to support this hypothesis.
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Authors | Sanjeewa Gamagedara, Stephen Gibbons, Yinfa Ma |
Journal | Clinica chimica acta; international journal of clinical chemistry
(Clin Chim Acta)
Vol. 412
Issue 1-2
Pg. 120-8
(Jan 14 2011)
ISSN: 1873-3492 [Electronic] Netherlands |
PMID | 20869359
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2010 Elsevier B.V. All rights reserved. |
Chemical References |
- Biomarkers
- Pteridines
- Creatinine
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Topics |
- Adult
- Aged
- Biomarkers
(chemistry, urine)
- Case-Control Studies
- Creatinine
(urine)
- Humans
- Middle Aged
- Neoplasms
(diagnosis, urine)
- Pteridines
(chemistry, urine)
- Young Adult
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