Fatal tuberculous myositis in an immunocompromised adult with primary Sjögren's syndrome.

Abstract

Tuberculous myositis, which mimics rheumatic symptoms, is an extremely rare disease. Clinical ambiguity easily leads to misdiagnosis and delayed initial treatment. We present the case of a 55-year-old man who had primary Sjögren's syndrome and active cutaneous vasculitis treated with steroid and immunosuppressive drugs. He presented with a swollen, painful, hot left thigh. Although anti-tuberculosis medications were administered soon after a positive acid-fast stain of incisional muscular tissue, he died of rapidly progressive tuberculous myositis and multiorgan failure following 18 days of hospitalization. This case is presented to increase the awareness of this rare entity in clinical practice.

• Authors: Chi-Chang Huang, Ming-Fei Liu, Nan-Yao Lee, Chia-Ming Chang, Hsin-Chun Lee, Chi-Jung Wu, Wen-Chien Ko
• Journal: Journal of the Formosan Medical Association = Taiwan yi zhi (J Formos Med Assoc) Vol. 109 Issue 9 Pg. 680-3 (Sep 2010) ISSN: 0929-6646 [Print] Singapore
• PMID: 20863997 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2010 Formosan Medical Association & Elsevier. Published by Elsevier B.V. All rights reserved.

Topics

• Biopsy
• Fatal Outcome
• Humans
• Immunocompromised Host
• Magnetic Resonance Imaging
• Male
• Middle Aged
• Muscle, Skeletal (microbiology, pathology)
• Myositis (etiology, pathology)
• Sjogren's Syndrome (complications, diagnosis)
• Tuberculosis (etiology, pathology)