Abstract | OBJECTIVE: METHODS: RESULTS: The mean resuscitation duration was (15.0±2.4) hours, and the volume of liquid resuscitation was 3 4594 203 ml, with mean volume (3 910± 102) ml in 22 patients; blood sodium (mmol/L) and chlorine (mmol/L) levels were both significantly higher after resuscitation compared with those before resuscitation (Na(+): 145.83±1.85 vs. 139.67±2.25, Cl(-): 117.33±1.64 vs. 101.83±1.77, both P<0.05). Blood pH value, hematocrit (Hct), anion gap (AG, mmol/L), blood lactic acid (mmol/L) were slightly lowered after resuscitation (pH value: 7.39±0.02 vs. 7.42±0.02, Hct: 35.63±1.58 vs. 46.85±2.38, AG: 8.02±1.21 vs. 14.47±0.89, blood lactic acid: 1.10±0.18 vs. 1.97±0.15, P<0.05 or P <0.01). In addition, the level of blood chlorine was significantly correlated with the volume of liquid used in resuscitation (r=0.720 8,P<0.01). CONCLUSION: The target of liquid resuscitation in patients with SAP should be cautiously determined, including control of the volume of liquid for resuscitation, in order to avoid acid-base imbalance or hyperchloraemia. At the same time, the change in internal environment should be monitored.
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Authors | Hai-bin Ni, Wei-qin Li, Lu Ke, Zhi-hui Tong, Xiao-fan Xu, Wei-wei Ding, Yao Nie |
Journal | Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
(Zhongguo Wei Zhong Bing Ji Jiu Yi Xue)
Vol. 22
Issue 9
Pg. 522-4
(Sep 2010)
ISSN: 1003-0603 [Print] China |
PMID | 20854729
(Publication Type: English Abstract, Journal Article, Research Support, Non-U.S. Gov't)
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Topics |
- Acid-Base Imbalance
- Adult
- Aged
- Female
- Fluid Therapy
- Homeostasis
- Humans
- Male
- Middle Aged
- Pancreatitis, Acute Necrotizing
(blood, physiopathology, therapy)
- Prospective Studies
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