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Testing pharmacogenetic indices to predict efficacy and toxicity of methotrexate monotherapy in a rheumatoid arthritis patient cohort.

AuthorsS A Owen, M Lunt, S L Hider, I N Bruce, A Barton, W Thomson
JournalArthritis and rheumatism (Arthritis Rheum) Vol. 62 Issue 12 Pg. 3827-9 (Dec 2010) ISSN: 1529-0131 [Electronic] United States
PMID20848569 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Antirheumatic Agents
  • Methotrexate
Topics
  • Antirheumatic Agents (adverse effects, therapeutic use)
  • Arthritis, Rheumatoid (drug therapy, genetics)
  • Cohort Studies
  • Dose-Response Relationship, Drug
  • Genotype
  • Humans
  • Logistic Models
  • Methotrexate (adverse effects, therapeutic use)
  • Pharmacogenetics
  • Predictive Value of Tests
  • Treatment Outcome

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