Outcomes with the use of bioprosthetic grafts to reinforce the ligation of the intersphincteric fistula tract (BioLIFT procedure) for the management of complex anal fistulas.

This study was undertaken to determine the outcomes of patients whose complex anal fistulas were managed by ligation of the intersphincteric fistula tract reinforced with a bioprosthetic graft (BioLIFT procedure).
A retrospective analysis was performed of all patients whose anal fistula was managed by use of the BioLIFT technique between May 2005 and May 2008, who had a minimum of 1 year of follow-up after their last treatment.
The BioLIFT technique using a bioprosthetic graft was used to treat a complex anal fistula in 31 patients (22 men, 9 women; mean age, 48 y (range, 30-68 y). Clinical healing of the fistula, defined as the absence of drainage with no evidence of residual fistula tract, occurred in 29 (94%) patients. No complications occurred that required intervention.
The BioLIFT procedure is effective for the management of complex fistulas-in-ano. Randomized clinical trials comparing this technique with other sphincter-preserving methods for fistula management need to be performed to further determine the role of this technique in the management of anal fistulas.
AuthorsC Neal Ellis
JournalDiseases of the colon and rectum (Dis Colon Rectum) Vol. 53 Issue 10 Pg. 1361-4 (Oct 2010) ISSN: 1530-0358 [Electronic] United States
PMID20847616 (Publication Type: Journal Article)
  • Adult
  • Aged
  • Anal Canal (surgery)
  • Bioprosthesis
  • Cohort Studies
  • Female
  • Humans
  • Ligation (instrumentation, methods)
  • Male
  • Middle Aged
  • Rectal Fistula (etiology, pathology, surgery)
  • Retrospective Studies
  • Suture Techniques (instrumentation)
  • Treatment Outcome

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