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Treating erosive lichen planus with griseofulvin: a report of four cases.

Abstract
Lichen planus is one of the most common dermatologic diseases involving the skin and oral mucous membranes. It may occur anywhere in the oral cavity. Erosive lichen planus has been reported to undergo malignant transformation, making definitive diagnosis, treatment, and followup essential. The purpose of this study was to establish the effectiveness of griseofulvin therapy on erosive lichen planus and to provide an alternative to steroid therapy. The results of this study revealed that griseofulvin had little or no effect on pain, pigmentation, or disappearance of erosive lichen planus and did not protect the patient from further recurrences.
AuthorsG D Naylor
JournalQuintessence international (Berlin, Germany : 1985) (Quintessence Int) Vol. 21 Issue 12 Pg. 943-7 (Dec 1990) ISSN: 0033-6572 [Print] GERMANY
PMID2082422 (Publication Type: Journal Article)
Chemical References
  • Griseofulvin
Topics
  • Adult
  • Aged
  • Female
  • Griseofulvin (therapeutic use)
  • Humans
  • Lichen Planus (drug therapy)
  • Male
  • Middle Aged
  • Mouth Diseases (drug therapy)
  • Pain
  • Recurrence

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