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Blockade of Janus kinase 2 signaling ameliorates mouse liver damage due to ischemia and reperfusion.

AuthorsRicky H Bhogal, Simon C Afford
JournalLiver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society (Liver Transpl) Vol. 16 Issue 9 Pg. 1112-3; author reply 114-5 (Sep 2010) ISSN: 1527-6473 [Electronic] United States
PMID20818749 (Publication Type: Comment, Letter)
Chemical References
  • Protein Kinase Inhibitors
  • Tyrphostins
  • alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide
  • Jak2 protein, mouse
  • Janus Kinase 2
Topics
  • Animals
  • Cell Line, Tumor
  • Disease Models, Animal
  • Hepatocytes (drug effects, enzymology, immunology)
  • Janus Kinase 2 (antagonists & inhibitors, metabolism)
  • Liver Diseases (enzymology, immunology, prevention & control)
  • Mice
  • Mice, Inbred C57BL
  • Protein Kinase Inhibitors (pharmacology)
  • Reperfusion Injury (enzymology, immunology, prevention & control)
  • Signal Transduction (drug effects)
  • Tyrphostins (pharmacology)

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