Pyogenic ventriculitis complicating Aggregatibacter aphrophilus infective endocarditis: A case report and literature review.

Abstract

Pyogenic ventriculitis (PV) is an uncommon, but frequently fatal infection that results from inflammation of the ventricular ependymal lining associated with a purulent ventricular system. PV has been rarely reported as a secondary complication of infective endocarditis. Prompt diagnosis and treatment with appropriate culture-directed antibiotics with adequate central nervous system penetration is crucial when managing patients who are suspected of having PV. The present study reports on a fatal case of a previously well 42-year-old alcoholic woman with infective endocarditis caused by Aggregatibacter aphrophilus, with secondary brain abscess and spontaneous rupture into the ventricles causing PV.

• Authors: Gordon W Jung, Michael D Parkins, Deirdre Church
• Journal: The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale (Can J Infect Dis Med Microbiol) Vol. 20 Issue 3 Pg. e107-9 ( 2009) ISSN: 1918-1493 [Electronic] Egypt
• PMID: 20808450 (Publication Type: Case Reports)