Leukocyte adhesion deficiency type 1 presenting with recurrent pyoderma gangrenosum and flaccid scarring.

Abstract

We report an 11-year-old boy with a longstanding history of recurrent pyoderma gangrenosum and abnormal wound healing who eventually developed a fatal invasive fungal infection. This article emphasizes the importance to consider leukocyte adhesion deficiency type 1 in the differential diagnosis of patients with recurrent skin ulcers.

• Authors: Claas H Hinze, Anne W Lucky, Kevin E Bove, Rebecca A Marsh, Jack H Bleesing, Murray H Passo
• Journal: Pediatric dermatology (Pediatr Dermatol) Vol. 27 Issue 5 Pg. 500-3 ( 2010) ISSN: 1525-1470 [Electronic] United States
• PMID: 20807363 (Publication Type: Case Reports, Journal Article)
• Copyright: © 2010 Wiley Periodicals, Inc.

Topics

• Biopsy
• Child
• Cicatrix (etiology, immunology, pathology)
• Fatal Outcome
• Humans
• Leukocyte-Adhesion Deficiency Syndrome (complications, immunology, pathology)
• Male
• Pyoderma Gangrenosum (complications, immunology, pathology)
• Recurrence
• Skin (immunology, pathology)