Efficacy of wide-field digital retinal imaging for retinopathy of prematurity screening.

Abstract

BACKGROUND:

To evaluate the efficacy of wide-field digital retinal imaging for retinopathy of prematurity screening.

DESIGN:

Retrospective study in a quaternary public neonatal intensive care unit.

PARTICIPANTS:

A total of 108 premature infants screened for retinopathy of prematurity.

METHODS:

Retrospective chart and photo review were performed on participants screened by both serial wide-field digital retinal imaging and concurrent binocular indirect ophthalmoscopy. Review of captured digital photos was performed independently by a masked reader. Using the binocular indirect ophthalmoscopy findings as the gold standard, the efficacy of wide-field digital retinal imaging in detecting treatment-requiring retinopathy of prematurity, defined as type 1 prethreshold disease, was determined.

MAIN OUTCOME MEASURES:

Sensitivity and specificity of wide-field digital retinal imaging in detecting treatment-requiring retinopathy of prematurity.

RESULTS:

Treatment-requiring retinopathy of prematurity was detected in 11 infants by both binocular indirect ophthalmoscopy examination and telemedicine images taken at the same visit. Wide-field digital retinal imaging has a sensitivity of 100% (95% CI: 76.2-100%) and a specificity of 97.9% (95% CI: 93.4-99.7%) in detecting infants with treatment-requiring retinopathy of prematurity. Positive and negative predictive values of wide-field digital retinal imaging were 84.6% (95% CI: 57.8-97.3%) and 100% (95% CI: 96.9-100%), respectively.

CONCLUSIONS:

Wide-field digital retinal imaging is accurate, reliable and efficient in detecting treatment-requiring retinopathy of prematurity. Incorporating wide-field digital retinal imaging with telemedicine in standard retinopathy of prematurity management can potentially improve delivery, accessibility, quality and cost of retinopathy of prematurity care.

• Authors: Shuan Dai, Kent Chow, Andrea Vincent
• Journal: Clinical & experimental ophthalmology (Clin Exp Ophthalmol) Vol. 39 Issue 1 Pg. 23-9 (Jan 2011) ISSN: 1442-9071 [Electronic] Australia
• PMID: 20796264 (Publication Type: Journal Article)
• Copyright: © 2010 The Authors. Clinical and Experimental Ophthalmology © 2010 Royal Australian and New Zealand College of Ophthalmologists.

Topics

• Birth Weight
• False Positive Reactions
• Female
• Gestational Age
• Humans
• Image Processing, Computer-Assisted
• Infant, Newborn
• Infant, Premature
• Intensive Care Units, Neonatal
• Male
• Ophthalmoscopy
• Photography
• Predictive Value of Tests
• Reproducibility of Results
• Retina (pathology)
• Retinopathy of Prematurity (classification, diagnosis, therapy)
• Retrospective Studies
• Sensitivity and Specificity
• Telemedicine