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Electrochemical genotyping and detection of single-nucleotide polymorphisms based on junction-probe containing 2'-deoxyinosine.

Abstract
A novel electrochemical biosensor for the genotyping/detection of single-nucleotide polymorphisms (SNPs) of trace oral-cancer salivary DNA based on junction probes containing 2'-deoxyinosine (dI) residues is described.
AuthorsJing Zhang, Xiaoyan Wu, Pingping Chen, Ningting Lin, Jinghua Chen, Guonan Chen, Fengfu Fu
JournalChemical communications (Cambridge, England) (Chem Commun (Camb)) Vol. 46 Issue 37 Pg. 6986-8 (Oct 7 2010) ISSN: 1364-548X [Electronic] England
PMID20730202 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Oligonucleotide Probes
  • Inosine
  • DNA
  • deoxyinosine
Topics
  • Biosensing Techniques
  • DNA (chemistry, genetics)
  • Electrochemistry
  • Genotype
  • Inosine (analogs & derivatives, chemistry, genetics)
  • Oligonucleotide Probes (chemistry, genetics)
  • Polymorphism, Single Nucleotide (genetics)

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