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PET for radiation treatment planning of brain tumours.

Abstract
AA-PET (MET-PET and FET-PET) can be used for gross tumour volume (GTV) delineation in brain gliomas and for the differentiation between treatment-related changes (pseudo-progression, pseudo-regression) and residual/recurrent tumour. There are some data showing that MET-PET and (DOTATOC)-PET can be used for GTV delineation in meningiomas and glomus tumours. The role of PET in the visualization of the biological characteristics of the tumours: proliferation (FLT-PET), hypoxia (FMISO-PET) and angiogenesis/peptide expression (RGD-PET) should be investigated in future studies.
AuthorsAnca-L Grosu, Wolfgang A Weber
JournalRadiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology (Radiother Oncol) Vol. 96 Issue 3 Pg. 325-7 (Sep 2010) ISSN: 1879-0887 [Electronic] Ireland
PMID20728952 (Publication Type: Journal Article, Review)
CopyrightCopyright 2010 European Society for Therapeutic Radiology and Oncology and European Association of Nuclear Medicine. Published by Elsevier Ireland Ltd.. All rights reserved.
Topics
  • Brain Neoplasms (diagnostic imaging, pathology, radiotherapy)
  • Humans
  • Positron-Emission Tomography (methods)
  • Radiotherapy Planning, Computer-Assisted (methods)

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