Abstract |
A 60-year-old male patient was diagnosed as bile duct cancer with left neck and abdominal para-aortic lymph node metastasis. He was treated by combined chemotherapy of S-1 and gemcitabine(GEM). S-1 (120 mg/day) was administered 14 days followed by 14 days rest as one course. GEM (1,000 mg/m2) was administered at 8 and 15 days after the start of S-1. Combined therapy could be continued, though S-1 and GEM were reduced for neutropemia. After 5 courses of treatment, CT and MRCP revealed a partial response. S-1/GEM combined therapy was effective for inoperable biliary tract carcinoma.
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Authors | Nobuhiro Akiyama, Sakura Ayata, Yuzuru Maruyama, Yoshihisa Tsukada |
Journal | Gan to kagaku ryoho. Cancer & chemotherapy
(Gan To Kagaku Ryoho)
Vol. 37
Issue 8
Pg. 1591-3
(Aug 2010)
ISSN: 0385-0684 [Print] Japan |
PMID | 20716894
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Drug Combinations
- Deoxycytidine
- S 1 (combination)
- Tegafur
- Oxonic Acid
- Gemcitabine
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Topics |
- Antineoplastic Combined Chemotherapy Protocols
(therapeutic use)
- Bile Duct Neoplasms
(diagnostic imaging, drug therapy)
- Deoxycytidine
(administration & dosage, analogs & derivatives, therapeutic use)
- Drug Combinations
- Fatal Outcome
- Humans
- Lymphatic Metastasis
(diagnostic imaging)
- Male
- Oxonic Acid
(administration & dosage, therapeutic use)
- Tegafur
(administration & dosage, therapeutic use)
- Tomography, X-Ray Computed
- Gemcitabine
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