HOMEPRODUCTSSERVICESCOMPANYCONTACTFAQResearchDictionaryPharmaMobileSign Up FREE or Login

Forty years of monensin for the control of coccidiosis in poultry.

Abstract
In July 1971, the polyether ionophorous antibiotic monensin was introduced in the United States for the control of coccidiosis in poultry. At that time, prospects for new anticoccidial agents were not good. Amprolium had enjoyed several years of use, but many other compounds had been abandoned as resistance to them developed. After the introduction of monensin, most commercial broilers were medicated with the drug and it is still widely used for this purpose today. Apart from in poultry, monensin is also used to control coccidiosis in game birds, sheep, and cattle. Indeed, more animals have been medicated with ionophores, such as monensin, for control of disease than any other medicinal agents in the history of veterinary medicine. In this review, we discuss the discovery, mode of action, and efficacy of monensin, together with matters of importance to the poultry industry such as commercial use, drug resistance, toxicity, pharmacology and residues, host immunity to coccidiosis, and effects in other avian species.
AuthorsH D Chapman, T K Jeffers, R B Williams
JournalPoultry science (Poult Sci) Vol. 89 Issue 9 Pg. 1788-801 (Sep 2010) ISSN: 0032-5791 [Print] United States
PMID20709963 (Publication Type: Journal Article, Review)
Chemical References
  • Coccidiostats
  • Monensin
Topics
  • Animals
  • Coccidiosis (drug therapy, veterinary)
  • Coccidiostats (therapeutic use)
  • Drug Resistance
  • Monensin (chemistry, pharmacology, therapeutic use)
  • Poultry
  • Poultry Diseases (drug therapy)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!


Choose Username:
Email:
Password:
Verify Password: