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Inhibition of hematopoietic stem cell proliferation by hemoregulatory peptide pyroGlu-Glu-Asp-Cys-Lys (pEEDCK) provides protection against short-term neutropenia and long-term damage.

AuthorsW R Paukovits, M H Moser, R Rutter, J B Paukovits
JournalAnnals of the New York Academy of Sciences (Ann N Y Acad Sci) Vol. 628 Pg. 92-104 ( 1991) ISSN: 0077-8923 [Print] United States
PMID2069326 (Publication Type: Journal Article)
Chemical References
  • Growth Inhibitors
  • Oligopeptides
  • Cytarabine
  • hemoregulatory peptide 5b
  • Pyrrolidonecarboxylic Acid
Topics
  • Animals
  • Cell Division (drug effects)
  • Colony-Forming Units Assay
  • Cytarabine (toxicity)
  • Growth Inhibitors (pharmacology)
  • Hematopoiesis (drug effects, physiology)
  • Hematopoietic Stem Cells (cytology, drug effects)
  • Kinetics
  • Mice
  • Mice, Inbred BALB C
  • Neutropenia (chemically induced, prevention & control)
  • Oligopeptides (pharmacology, therapeutic use)
  • Pyrrolidonecarboxylic Acid (analogs & derivatives)

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