[Thiocyanate--a pathogenetic factor in cystic fibrosis (mucoviscidosis)?].

Abstract

Thiocyanate (SCN-) concentrations in serum samples of 32 cystic fibrosis (CF) patients, 30 controls as well as 23 heterozygotes (parents of CF patients) were investigated, because SCN- influenced viscosity of secretions, membrane functions as well as nonspecific and specific defense processes. CF patients showed little smaller SCN- serum levels, but the differences were not statistically significant. There were remarkable smaller values for CF patients with most serious clinical conditions due to severe pulmonary changes.

• Authors: W Weuffen, J Hein, H Below, H U Gülzow
• Journal: Padiatrie und Grenzgebiete (Padiatr Grenzgeb) Vol. 30 Issue 3 Pg. 205-10 ( 1991) ISSN: 0030-932X [Print] Germany
• Vernacular Title: Thiocyanat--ein pathogenetischer Faktor bei der zystischen Fibrose (Mukoviszidose)?
• PMID: 2067870 (Publication Type: Journal Article)

Chemical References

• Thiocyanates
• thiocyanate

Topics

• Adolescent
• Child
• Child, Preschool
• Cystic Fibrosis (blood, diagnosis, genetics)
• Genetic Carrier Screening
• Humans
• Lung (pathology)
• Prognosis
• Thiocyanates (blood)