HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

A randomized trial on root caries prevention in elders.

Abstract
Root caries is common in institutionalized elders, and effective prevention methods are needed. This clinical trial compared the effectiveness of four methods in preventing new root caries. From 21 residential homes, 306 generally healthy elders having at least 5 teeth with exposed sound root surfaces were randomly allocated into one of four groups: (1) individualized oral hygiene instruction (OHI); (2) OHI and applications of 1% chlorhexidine varnish every 3 months; (3) OHI and applications of 5% sodium fluoride varnish every 3 months; and (4) OHI and annual applications of 38% silver diamine fluoride (SDF) solution. Two-thirds (203/306) of the elders were followed for 3 years. Mean numbers of new root caries surfaces in the four groups were 2.5, 1.1, 0.9, and 0.7, respectively (ANOVA, p < 0.001). SDF solution, sodium fluoride varnish, and chlorhexidine varnish were more effective in preventing new root caries than giving OHI alone.
AuthorsH P Tan, E C M Lo, J E Dyson, Y Luo, E F Corbet
JournalJournal of dental research (J Dent Res) Vol. 89 Issue 10 Pg. 1086-90 (Oct 2010) ISSN: 1544-0591 [Electronic] United States
PMID20671206 (Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
Chemical References
  • Anti-Infective Agents, Local
  • Cariostatic Agents
  • Fluorides, Topical
  • Quaternary Ammonium Compounds
  • Silver Compounds
  • Toothpastes
  • Sodium Fluoride
  • silver diamine fluoride
  • Chlorhexidine
Topics
  • Aged
  • Anti-Infective Agents, Local (administration & dosage, therapeutic use)
  • Cariostatic Agents (therapeutic use)
  • Chlorhexidine (administration & dosage, therapeutic use)
  • DMF Index
  • Female
  • Fluorides, Topical (therapeutic use)
  • Follow-Up Studies
  • Humans
  • Institutionalization
  • Male
  • Nursing Homes
  • Oral Hygiene
  • Patient Education as Topic
  • Quaternary Ammonium Compounds (therapeutic use)
  • Residential Facilities
  • Root Caries (prevention & control)
  • Self Care
  • Silver Compounds
  • Sodium Fluoride (therapeutic use)
  • Toothbrushing (methods)
  • Toothpastes (therapeutic use)
  • Treatment Outcome

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: