[Catecholaminergic polymorphic ventricular tachycardia is a rare inherited heart disease].

Abstract

Catecholaminergic polymorphic ventricular tachycardia is a rare inherited heart disease, which can lead to life-threatening ventricular arrhythmias in patients with a structurally normal heart. The age of onset is usually between two and 12 years and the initial symptom is frequently syncope or cardiac arrest. The arrhythmias are usually triggered by exercise or emotional affection. The diagnosis is often made using exercise electrocardiogram, which typically triggers arrhythmias. The treatment consists of beta blockers, frequently in combination with implantation of a cardioverter-defibrillator.

• Authors: Anders Gaarsdal Holst, Jacob Tfelt-Hansen, Morten S Olesen, Juliane Theilade, Bo G Winkel, Alex H Christensen, Henning Bundgaard, Stig Haunsø, Jesper Hastrup Svendsen
• Journal: Ugeskrift for laeger (Ugeskr Laeger) Vol. 172 Issue 31 Pg. 2140-4 (Aug 02 2010) ISSN: 1603-6824 [Electronic] Denmark
• Vernacular Title: Katekolaminerg polymorf ventrikulaer takykardi er en sjaelden arvelig hjertesygdom.
• PMID: 20670590 (Publication Type: English Abstract, Journal Article, Review)

Chemical References

• Catecholamines
• Ryanodine Receptor Calcium Release Channel

Topics

• Catecholamines (physiology)
• Child
• Child, Preschool
• Diagnosis, Differential
• Heart Arrest (diagnosis)
• Humans
• Mutation
• Ryanodine Receptor Calcium Release Channel (genetics)
• Syncope (diagnosis)
• Tachycardia, Ventricular (congenital, diagnosis, therapy)