Genetic improvement of grass pea for low neurotoxin (β-ODAP) content.

Abstract

Grass pea is a promising crop for adaptation under climate change because of its tolerance to drought, water-logging and salinity, and being almost free from insect-pests and diseases. In spite of such virtues, global area under its cultivation has decreased because of ban on its cultivation in many countries. The ban is imposed due to its association with neurolathyrism, a non-reversible neurological disorder in humans and animals due to presence of neurotoxin, β-N-oxalyl-L-α,β-diaminopropionic acid (β-ODAP) in its seedlings and seeds. The traditional varieties of grass pea contain 0.5-2.5% β-ODAP. Exploitable genetic variability for β-ODAP has been observed for development of low ODAP varieties, which along with improved agronomic and detoxification practices can help reduce the risk of lathyrism. Collaborative efforts between ICARDA and NARS have resulted in development of improved varieties such as Wasie in Ethiopia, Ratan, Prateek and Mahateora in India, and BARI Khesari-1 and BARI Khesari-2 in Bangladesh with <0.10% β-ODAP. Soil application of 15-20 kg ha(-1) zinc sulphate, early planting, and soaking seeds in water have shown significant effects on β-ODAP. Because of the often cross-pollination nature, the current breeding procedures being followed in grass pea requires paradigm shift in its approach for a possible genetic breakthrough.

• Authors: Shiv Kumar, G Bejiga, S Ahmed, H Nakkoul, A Sarker
• Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association (Food Chem Toxicol) Vol. 49 Issue 3 Pg. 589-600 (Mar 2011) ISSN: 1873-6351 [Electronic] England
• PMID: 20659523 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: Copyright © 2010 Elsevier Ltd. All rights reserved.

Chemical References

• Amino Acids, Diamino
• Neurotoxins
• Soil
• oxalyldiaminopropionic acid
• Zinc Sulfate

Topics

• Amino Acids, Diamino (poisoning)
• Bangladesh
• Breeding
• Ethiopia
• Humans
• India
• Lathyrism (chemically induced)
• Lathyrus (genetics, poisoning)
• Mutation
• Neurotoxins (poisoning)
• Plants, Genetically Modified (genetics, poisoning)
• Seedlings (genetics, metabolism)
• Soil (chemistry)
• Zinc Sulfate (analysis)