Abstract | PURPOSE: MATERIALS AND METHODS: Literature selected from peer reviewed journals listed in MEDLINE(R)/PubMed(R) from 1943 to 2009 and from resources cited in those articles was reviewed comprehensively. RESULTS: CONCLUSIONS: Oral regimens for the treatment of gonorrhea are limited. At present to our knowledge ceftriaxone is the most reliable and available agent for the treatment of gonorrhea. To prevent the further emergence and international spread of drug resistance, and allow for the selection of appropriate treatments, a comprehensive global program is needed including surveillance for drug resistance in N. gonorrhoeae and collection of patient epidemiological data. Clinicians should effectively treat patients with gonorrhea, always being conscious of local trends of drug resistance in N. gonorrhoeae, and should perform culture and antimicrobial susceptibility testing in those with persistent gonorrhea after treatment.
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Authors | Takashi Deguchi, Keita Nakane, Mitsuru Yasuda, Shin-ichi Maeda |
Journal | The Journal of urology
(J Urol)
Vol. 184
Issue 3
Pg. 851-8; quiz 1235
(Sep 2010)
ISSN: 1527-3792 [Electronic] United States |
PMID | 20643433
(Publication Type: Journal Article, Review)
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Copyright | 2010 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved. |
Chemical References |
- Fluoroquinolones
- Azithromycin
- Cefixime
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Topics |
- Azithromycin
(pharmacology)
- Cefixime
(pharmacology)
- Drug Resistance, Bacterial
- Fluoroquinolones
(pharmacology)
- Gonorrhea
(drug therapy)
- Humans
- Neisseria gonorrhoeae
(drug effects)
- Population Surveillance
- Urethritis
(drug therapy, microbiology)
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