Abstract |
The clinical meaning of high values of blood lipid peroxides, assessed as thiobarbituric acid reactive substances (TBA-RS), was investigated in 19 selected high risk patients with transient ischemic attacks (TIA). Patients were checked every 3-6 months and followed-up for 3 years. 8 patients experienced further vascular episodes, 4 having minor stroke and 4 TIA; one of the latter died from myocardial infarction. Unlike blood cholesterol and glucose. TBA-RS values discriminated patients with vascular episodes: they, indeed, showed significant higher values of TBA-RS. Discriminant analysis further indicated that TBA-RS levels differentiate patients with and without vascular accidents, suggesting that high blood values of lipid peroxides could represent a predictive sign of vascular ischemia.
|
Authors | C Alessandri, M Germani, C Censi, G Rudelli, L Iuliano, M Servi, A Ghiselli, F Violi |
Journal | Acta neurologica Scandinavica
(Acta Neurol Scand)
Vol. 83
Issue 5
Pg. 323-7
(May 1991)
ISSN: 0001-6314 [Print] Denmark |
PMID | 2063655
(Publication Type: Journal Article)
|
Chemical References |
- Blood Glucose
- Lipid Peroxides
- Thiobarbiturates
- Triglycerides
- Cholesterol
- thiobarbituric acid
|
Topics |
- Aged
- Blood Glucose
(metabolism)
- Cerebral Infarction
(blood, diagnosis)
- Cholesterol
(blood)
- Female
- Follow-Up Studies
- Humans
- Intracranial Arteriosclerosis
(blood, diagnosis)
- Ischemic Attack, Transient
(blood, diagnosis)
- Lipid Peroxides
(blood)
- Male
- Middle Aged
- Recurrence
- Risk Factors
- Thiobarbiturates
(pharmacokinetics)
- Triglycerides
(blood)
|