[Circulating cell-free serum DNA: significance as a new biomarker for urological malignancies].

Abstract

The presence of circulating cell-free DNA was demonstrated already in the 1940s. Improved detection methods have led to increased knowledge on cell-free DNA, and recent studies showed that most cancer patients have increased levels of cell-free DNA. Measurement of cell-free DNA allowed sensitive and specific discrimination between cancer patients and those with non-malignant diseases.

• Authors: J Ellinger, A von Rücker, P J Bastian, S C Müller
• Journal: Der Urologe. Ausg. A (Urologe A) Vol. 49 Issue 9 Pg. 1131-2, 1134 (Sep 2010) ISSN: 1433-0563 [Electronic] Germany
• Vernacular Title: Zellfreie DNA im Blut : Bedeutung als neuer Biomarker für urologische Malignome.
• PMID: 20628864 (Publication Type: English Abstract, Journal Article)

Chemical References

• Biomarkers, Tumor
• DNA, Neoplasm

Topics

• Biomarkers, Tumor (blood)
• Cell-Free System
• DNA, Neoplasm (blood, genetics)
• Diagnostic Techniques, Urological
• Humans
• Urologic Neoplasms (diagnosis, genetics)