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Intravitreal bevacizumab in choroidal neovascularization associated with congenital choroidal and optic nerve coloboma in children: long-term improvement in visual acuity.

Abstract
Choroidal neovascular membranes are a rare cause of decreased vision in children with congenital choroidal and optic nerve colobomas. We report on the regression of coloboma-related choroidal neovascular membranes in 2 children treated with intravitreal bevacizumab. Visual acuity remained improved in both children 2 years after the last injection.
AuthorsPrashant Naithani, Naginder Vashisht, Subrata Mandal, Preeti Sankaran, Satpal Garg
JournalJournal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus (J AAPOS) Vol. 14 Issue 3 Pg. 288-90 (Jun 2010) ISSN: 1528-3933 [Electronic] United States
PMID20603066 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Angiogenesis Inhibitors
  • Antibodies, Monoclonal
  • Antibodies, Monoclonal, Humanized
  • Bevacizumab
Topics
  • Angiogenesis Inhibitors (administration & dosage)
  • Antibodies, Monoclonal (administration & dosage)
  • Antibodies, Monoclonal, Humanized
  • Bevacizumab
  • Child
  • Child, Preschool
  • Choroidal Neovascularization (complications, congenital, drug therapy)
  • Coloboma (complications)
  • Female
  • Humans
  • Injections, Intraocular
  • Optic Nerve (abnormalities)
  • Treatment Outcome
  • Visual Acuity (drug effects)

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