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[Da cheng qi tang on 45Ca content of the isolated colon smooth muscle from experimental colon obstruction rats].

Abstract
Da Cheng Qi Tang (DCQT) is a classical prescription of Chinese medicine for treatment of acute intestinal obstruction. In this paper, the isolated colon smooth muscle from normal and experimental colon obstruction (CO) rats were used to study the effect of DCQT on 45Ca content. The results showed that the 45Ca content on isolated colon smooth muscle (microns/g wet tissue, mean +/- S) was 0.043 +/- 0.009 in the normal and 0.057 +/- 0.012 in those treated by DCQT respectively. The content of 45Ca in CO was higher than the normal, DCQT can reduce the content of 45Ca in CO. It is known that the higher level of intracellular CA++ is related to the formation and the development of acute intestinal obstruction. The inhibitory effect of DCQT on 45Ca content may play an important role in the treatment of acute colon obstruction.
AuthorsY Kang, S Guo, X Z Wu
JournalZhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine (Zhong Xi Yi Jie He Za Zhi) Vol. 11 Issue 2 Pg. 107-9, 70 (Feb 1991) ISSN: 0254-9034 [Print] China
PMID2060051 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Drugs, Chinese Herbal
  • Calcium
Topics
  • Animals
  • Biological Transport, Active (drug effects)
  • Calcium (metabolism)
  • Colon (drug effects)
  • Drugs, Chinese Herbal (pharmacology)
  • Humans
  • In Vitro Techniques
  • Intestinal Obstruction (metabolism)
  • Muscle, Smooth (drug effects)
  • Rats
  • Rats, Inbred Strains

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