New technique using combined pulsed dye laser and fractional resurfacing for treating facial angiofibromas in tuberous sclerosis.

Abstract

BACKGROUND AND OBJECTIVE:

Tuberous sclerosis (TS) is a well-described genetic disorder that is classically associated with up to hundreds of facial angiofibromas. Due to the progressive nature of the skin lesions and the early clinical presentation, a safe and effective technique for treating these disfiguring skin lesions is needed.

STUDY DESIGN/PATIENTS AND METHODS:

We report a combinatorial technique for treating the angiofibromas of TS. We present a case series of three TS patients treated with this technique combining pinpoint electrosurgery, pulsed-dye laser treatment, and ablative fractional resurfacing (AFR).

RESULTS:

In all presented cases, improvement in the number and appearance of facial angiofibromas and erythema is noted. No scarring or adverse events were reported.

CONCLUSION:

The technique of electrosurgery, pulsed-dye laser treatment, and AFR represents a new and safe therapeutic option for treating facial angiofibromas associated with TS.

• Authors: Elliot T Weiss, Roy G Geronemus
• Journal: Lasers in surgery and medicine (Lasers Surg Med) Vol. 42 Issue 5 Pg. 357-60 (Jul 2010) ISSN: 1096-9101 [Electronic] United States
• PMID: 20583249 (Publication Type: Case Reports, Journal Article)

Topics

• Adolescent
• Adult
• Angiofibroma (etiology, surgery)
• Facial Neoplasms (etiology, surgery)
• Humans
• Laser Therapy (methods)
• Lasers, Dye (therapeutic use)
• Male
• Skin Neoplasms (etiology, surgery)
• Tuberous Sclerosis (complications)