Abstract | AIM: MATERIALS AND METHODS: A retrospective case-control study of 207 consecutive patients (45.8% male mean age 64.0 years), 150 with asymptomatic diverticulosis, and 57 with acute diverticulitis. Diagnosis of diverticulosis was defined on the basis of clinical and colonoscopic criteria, diverticulitis was defined by means of clinical, colonoscopic and computerised tomography criteria. Logistic regression function was used to define the relationship between the dependent variable ( diverticulitis) and several covariates: sex, age, body mass index, smoking habit, and history of appendectomy. RESULTS: According to the final model, the risk of diverticulitis was 4.94-fold higher (95% confidence interval: 1.98-12.37) in patients with a history of appendectomy with emergency resection, compared to patients not submitted to appendectomy or with a history of elective resection (P < 0.001); and 2.79-fold higher (95% confidence interval: 1.30-5.96) in smokers than in non-smokers (P = 0.008). The effects of the two determinants were found to be independent, thus the cumulative risk of diverticulitis was 13.78-fold higher for smokers with a history of emergency surgical treatment. CONCLUSION:
|
Authors | Paolo Usai, Ivan Ibba, Mariantonia Lai, Maria Francesca Boi, Maria Flavia Savarese, Rosario Cuomo, Giuseppe D'Alia, Sergio Gemini, Giacomo Diaz, Paolo Contu |
Journal | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
(Dig Liver Dis)
Vol. 43
Issue 2
Pg. 98-101
(Feb 2011)
ISSN: 1878-3562 [Electronic] Netherlands |
PMID | 20579946
(Publication Type: Journal Article)
|
Copyright | Copyright © 2010 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved. |
Topics |
- Adult
- Aged
- Aged, 80 and over
- Appendectomy
(adverse effects)
- Confidence Intervals
- Diverticulitis
(diagnosis, etiology)
- Diverticulum
(complications, diagnosis)
- Emergency Treatment
- Female
- Humans
- Logistic Models
- Male
- Middle Aged
- Prognosis
- Risk Factors
- Smoking
(adverse effects)
|