HLA alleles and fissured tongue.

Abstract

The aim of this study was to investigate the linkage between HLA and fissured tongue. Sixty- nine individuals with fissured tongue and 125 healthy volunteers were typed for HLA-DRB1*. The results showed increased frequency of HLA-DRB1*08 (P < 0.001), HLA-DRB1*14 (P < 0.01), HLA-DRB1*11 (P < 0.05) and HLA-DRB1*16 (P < 0.05), while HLA-DRB1*03 and HLA-DRB1*07 frequency was decreased (P < 0.05).

• Authors: A Kalifatidis, E Albanidou-Farmaki, M Daniilidis, A K Markopoulos, N Karyotis, D Z Antoniades
• Journal: International journal of immunogenetics (Int J Immunogenet) Vol. 37 Issue 6 Pg. 509-11 (Dec 2010) ISSN: 1744-313X [Electronic] England
• PMID: 20572893 (Publication Type: Journal Article)
• Copyright: © 2010 Blackwell Publishing Ltd.

Chemical References

• HLA Antigens
• HLA-DR Antigens
• HLA-DRB1 Chains

Topics

• Alleles
• Chi-Square Distribution
• Female
• Gene Frequency
• Genes, Dominant
• Genetic Linkage
• Genetic Predisposition to Disease
• Greece
• HLA Antigens (genetics)
• HLA-DR Antigens (genetics)
• HLA-DRB1 Chains
• Haplotypes
• Histocompatibility Testing
• Humans
• Male
• Polymerase Chain Reaction
• Tongue, Fissured (genetics)