Comparative study between chitin/polyacrylic acid (PAA) dressing, lipido-colloid absorbent dressing and alginate wound dressing: a pilot study in the treatment of partial-thickness wound.

Abstract

BACKGROUND:

Polyacrylic acid grafted chitin (Chitin-PAA) contains a hydrogel characteristic that makes it more suitable for wound dressing application. In animal models, Chitin-PAA dressing exhibited properties as a promising dressing. Epithelization promotion, rapid reduction of wound size, reduction of inflammatory cell response, and less toxicity had been noted.

OBJECTIVE:

Carryout a pilot clinical comparative study of Chitin-PAA dressing, lipido-colloid absorbent dressing, and alginate wound dressing in the treatment of partial-thickness wound.

MATERIAL AND METHOD:

Between June 2006 and March 2007, 36 partial-thickness wounds were randomized into three groups and three different types of dressing were used. Each wound was treated until it was completely healed, and a visual analogue scale was used for the pain evaluation.

RESULT:

The present study shows the visual analogue pain score in the Chitin-PAA group seems to be a bit higher than the Urgocell group but not statistically different. The completely healed day is not significantly different. Three patients in the lipido-colloid absorbent dressing groups had wound infection but eventually healed after treatment.

CONCLUSION:

There was no statistical difference in terms of visual analogue pain score and healing time between the lipido-colloid absorbent dressing, alginate dressing, and chitin-PAA dressing.

• Authors: Apichai Angspatt, Puttan Tanvatcharaphan, Somruethai Channasanon, Siriporn Tanodekaew, Prayuth Chokrungvaranont, Wimol Sirimaharaj
• Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet (J Med Assoc Thai) Vol. 93 Issue 6 Pg. 694-7 (Jun 2010) ISSN: 0125-2208 [Print] Thailand
• PMID: 20572374 (Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)

Chemical References

• Acrylic Resins
• Alginates
• Biocompatible Materials
• Chitin
• carbopol 940

Topics

• Acrylic Resins (therapeutic use)
• Adult
• Aged
• Alginates (therapeutic use)
• Bandages
• Biocompatible Materials (therapeutic use)
• Chitin (therapeutic use)
• Female
• Humans
• Male
• Middle Aged
• Pain Measurement
• Pilot Projects
• Treatment Outcome
• Wound Healing
• Wounds and Injuries (therapy)
• Young Adult