Abstract |
BACKGROUND.: The purpose of this study was to assess the usefulness of contrast-enhanced sonography (CEUS) with Sonazoid to demonstrate local recurrence of hepatocellular carcinoma previously treated with radiofrequency ablation (RFA) and not seen on conventional sonography, prior to repeat RFA. METHODS.: This study included 16 cirrhotic patients with 17 cases of hypervascular locally recurrent hepatocellular carcinoma found by contrast-enhanced multidetector row CT (MDCT) but not seen on noncontrast sonography. We used Kupffer-phase imaging and vascular-phase imaging after re-injection. The morphologic patterns of local recurrence detected on CEUS were compared with those on MDCT. We performed repeat RFA guided by CEUS using Kupffer-phase imaging after re-injection. RESULTS.: We were able to detect on CEUS the location of all local recurrences with positive enhancement after re-injection. The morphologic patterns of local recurrence on CEUS were in concordance with those found on MDCT in all lesions. Repeat percutaneous RFA was successfully performed in all lesions. CONCLUSIONS.: The CEUS appearance of local recurrences correlated well with those on MDCT. A wider use of CEUS to guide repeat of percutaneous RFA may be possible with Sonazoid.
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Authors | Noriyuki Miyamoto, Kazuhide Hiramatsu, Kazuhiko Tsuchiya, Yukihiko Sato |
Journal | Journal of clinical ultrasound : JCU
(J Clin Ultrasound)
Vol. 38
Issue 7
Pg. 339-45
(Sep 2010)
ISSN: 1097-0096 [Electronic] United States |
PMID | 20572066
(Publication Type: Journal Article)
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Chemical References |
- Contrast Media
- Ferric Compounds
- Oxides
- Sonazoid
- Iron
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Topics |
- Aged
- Aged, 80 and over
- Carcinoma, Hepatocellular
(diagnostic imaging, surgery)
- Catheter Ablation
(methods)
- Contrast Media
- Female
- Ferric Compounds
- Follow-Up Studies
- Humans
- Image Enhancement
(methods)
- Image Processing, Computer-Assisted
(methods)
- Iron
- Liver
(diagnostic imaging)
- Liver Neoplasms
(diagnostic imaging, surgery)
- Male
- Middle Aged
- Neoplasm Recurrence, Local
(diagnostic imaging, surgery)
- Oxides
- Treatment Outcome
- Ultrasonography
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