Abstract | OBJECTIVE: Description of the clinical response of 12 consecutive cases of disease-active ankylosing spondylitis (AS) treated with the herbal medicine Tripterygium wilfordii Hook f (TwHf; lei gong teng, thunder god vine), which has been reported in controlled studies to be effective in rheumatoid arthritis (RA). METHODS: The clinical status of 12 patients with active AS who were started on 60 mgday(-1) of a commercial tablet preparation of TwHf extract. were monitored at weeks 1, 3, and 6. RESULTS: CONCLUSION: A placebo-controlled double-blind study for Tripterygium is warranted. Until then, this particular report should be considered as case reports and not an endorsement of the use of Tripterygium in clinical practice.
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Authors | Wei Ji, Juan Li, Yue Lin, Ya-Nan Song, Miaojia Zhang, Yao Ke, Yile Ren, Xiaohu Deng, Jianglin Zhang, Feng Huang, David Yu |
Journal | Clinical rheumatology
(Clin Rheumatol)
Vol. 29
Issue 9
Pg. 1067-72
(Sep 2010)
ISSN: 1434-9949 [Electronic] Germany |
PMID | 20563618
(Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Administration, Oral
- Adult
- Dose-Response Relationship, Drug
- Female
- Humans
- Male
- Middle Aged
- Phytotherapy
(methods)
- Plant Preparations
(administration & dosage, therapeutic use)
- Spondylitis, Ankylosing
(drug therapy)
- Treatment Outcome
- Tripterygium
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