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Immunohistochemical localization of IGF-I, IGF-II and MSTN proteins during development of triploid sea bass (Dicentrarchus labrax).

Abstract
The cellular localization of IGF-I, IGF-II and MSTN proteins was investigated during ontogenesis of triploid sea bass (Dicentrarchus labrax) by an immunohistochemical approach. The results were compared with those observed in diploids. IGF-I immunostaining was mainly observed in skin, skeletal muscle, intestine and gills of both diploids and triploids. From day 30 of larval life, IGF-I immunoreactivity observed in skeletal muscle, intestine, gills and kidney was stronger in triploids than in diploids. At day 30, triploids exhibited a standard length significantly higher than the one of diploids. Although IGF-II and MSTN immunoreactivity was detectable in different tissues and organs, no differences between diploids and triploids were observed. The spatial localization of IGF-I, IGF-II and MSTN proteins detected in this study is in agreement with previous findings on the distribution of these proteins in diploid larvae and fry. The highest IGF-I immunoreactivity observed in triploids suggests a possible involvement of ploidy in their growth performance.
AuthorsG Radaelli, C Poltronieri, C Simontacchi, E Negrato, F Pascoli, A Libertini, D Bertotto
JournalEuropean journal of histochemistry : EJH (Eur J Histochem) Vol. 54 Issue 2 Pg. e16 (Apr 14 2010) ISSN: 2038-8306 [Electronic] Italy
PMID20558336 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Myostatin
  • Insulin-Like Growth Factor I
  • Insulin-Like Growth Factor II
Topics
  • Animals
  • Bass (growth & development, metabolism)
  • Immunohistochemistry
  • Insulin-Like Growth Factor I (metabolism)
  • Insulin-Like Growth Factor II (metabolism)
  • Myostatin (metabolism)

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