Abstract | OBJECTIVE: DATA SOURCES: Literature retrieval was accessed through MEDLINE/PubMed (1950-March 2010), Web of Science (1980-March 2010), and International Pharmaceutical Abstracts (1977-March 2010) using the terms colesevelam, dyslipidemia, hypercholesterolemia, and type 2 diabetes mellitus. References from publications identified were reviewed for additional resources. In addition, abstracts presented at the most recent (2009) American Diabetes Association, American Association of Clinical Endocrinologists, and European Association for the Study of Diabetes annual meetings were searched for relevant original research. STUDY SELECTION AND DATA EXTRACTION: All articles in English identified from the data sources were evaluated. All relevant studies evaluating the safety and efficacy of colesevelam in hypercholesterolemia and/or type 2 diabetes mellitus were included. Priority was placed on data obtained from human randomized controlled trials. DATA SYNTHESIS: CONCLUSIONS:
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Authors | Luigi Brunetti, Evelyn R Hermes-Desantis |
Journal | The Annals of pharmacotherapy
(Ann Pharmacother)
2010 Jul-Aug
Vol. 44
Issue 7-8
Pg. 1196-206
ISSN: 1542-6270 [Electronic] United States |
PMID | 20551301
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)
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Chemical References |
- Anticholesteremic Agents
- Allylamine
- Colesevelam Hydrochloride
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Topics |
- Allylamine
(adverse effects, analogs & derivatives, therapeutic use)
- Anticholesteremic Agents
(adverse effects, therapeutic use)
- Clinical Trials as Topic
- Colesevelam Hydrochloride
- Diabetes Mellitus, Type 2
(complications, drug therapy)
- Drug Therapy, Combination
- Humans
- Hypercholesterolemia
(complications, drug therapy)
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