Suppression of ventricular tachycardia with dronedarone: a case report.

Abstract

UNLABELLED:

 

INTRODUCTION:

Dronedarone is a multichannel blocker with similar electrophysiological properties to amiodarone. Dronedarone has not been studied in humans as an agent to suppress ventricular arrhythmias.

METHODS:

This case report describes the dramatic antiarrhythmic effects of dronedarone in a patient with nonischemic cardiomyopathy and recurrent ventricular tachycardia, which was resistant to multiple antiarrhythmic agents and endocardial catheter ablation.

RESULTS:

Dronedarone was effective in completely suppressing ventricular tachycardia.

CONCLUSION:

Further research is needed to establish a potential larger role for dronedarone in controlling ventricular arrhythmias in humans.

• Authors: Mustaphasahim Shaaraoui, Ronald Freudenberger, Vadim Levin, Francis E Marchlinski
• Journal: Journal of cardiovascular electrophysiology (J Cardiovasc Electrophysiol) Vol. 22 Issue 2 Pg. 201-2 (Feb 2011) ISSN: 1540-8167 [Electronic] United States
• PMID: 20550612 (Publication Type: Case Reports, Journal Article)
• Copyright: © 2010 Wiley Periodicals, Inc.

Chemical References

• Anti-Arrhythmia Agents
• Dronedarone
• Amiodarone

Topics

• Adult
• Amiodarone (analogs & derivatives, therapeutic use)
• Anti-Arrhythmia Agents (therapeutic use)
• Cardiomyopathies (complications, diagnosis, prevention & control)
• Dronedarone
• Humans
• Male
• Secondary Prevention
• Tachycardia, Ventricular (complications, diagnosis, prevention & control)
• Treatment Outcome