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Mepolizumab does not alter levels of eosinophils, T cells, and mast cells in the duodenal mucosa in eosinophilic esophagitis.

AuthorsSébastien Conus, Alex Straumann, Eva Bettler, Hans-Uwe Simon
JournalThe Journal of allergy and clinical immunology (J Allergy Clin Immunol) Vol. 126 Issue 1 Pg. 175-7 (Jul 2010) ISSN: 1097-6825 [Electronic] United States
PMID20542323 (Publication Type: Letter, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
Chemical References
  • Antibodies, Monoclonal
  • Antibodies, Monoclonal, Humanized
  • Interleukin-5
  • mepolizumab
Topics
  • Adult
  • Antibodies, Monoclonal (pharmacology, therapeutic use)
  • Antibodies, Monoclonal, Humanized
  • Duodenum (pathology)
  • Eosinophilia (drug therapy, immunology)
  • Eosinophils (drug effects)
  • Esophagitis (drug therapy, immunology)
  • Female
  • Humans
  • Interleukin-5 (antagonists & inhibitors)
  • Intestinal Mucosa (pathology)
  • Male
  • Mast Cells (drug effects)
  • T-Lymphocytes (drug effects)

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