Treatment of renal artery fibromuscular dysplasia.

Abstract

Fibromuscular dysplasia is a nonatherosclerotic and noninflammatory disease that can result in stenoses of the renal arteries and hypertension, most commonly affecting middle-aged women. Percutaneous transluminal angioplasty has long been considered the mainstay of therapy and offers high rates of improved or cured hypertension. The disease involves the mid and distal renal arteries and branchpoints and poses endovascular treatment challenges that separate fibromuscular dysplasia from atherosclerotic disease. The development of smaller balloon dilation systems offers safe and highly effective endovascular treatment options for technically difficult lesions. Newer technologies such as cutting balloons also add to the armamentarium of treatment choices, which may be useful in the setting of resistant stenoses. This article focuses on the modern technical considerations in the diagnostic evaluation and endovascular treatment of renal artery fibromuscular dysplasia.

• Authors: Michael A Meuse, Ulku C Turba, Saher S Sabri, Auh-Whan Park, Wael E A Saad, J Fritz Angle, Alan H Matsumoto
• Journal: Techniques in vascular and interventional radiology (Tech Vasc Interv Radiol) Vol. 13 Issue 2 Pg. 126-33 (Jun 2010) ISSN: 1557-9808 [Electronic] United States
• PMID: 20540921 (Publication Type: Journal Article, Review)
• Copyright: Copyright 2010 Elsevier Inc. All rights reserved.

Topics

• Angiography, Digital Subtraction
• Angioplasty, Balloon (instrumentation)
• Equipment Design
• Fibromuscular Dysplasia (complications, diagnostic imaging, therapy)
• Humans
• Radiography, Interventional
• Renal Artery Obstruction (diagnostic imaging, etiology, therapy)
• Tomography, X-Ray Computed
• Treatment Outcome