Abstract |
A 27-year-old female was admitted to Sendai National Hospital complaining of continuous slight genital bleeding for about one and a half year after incomplete abortion. At first visit, urinary hCG was elevated to 32,000 IU/l and ultrasonography revealed a heterogeneous tumor in the uterus body. After abdominal simple total hysterectomy, the sample was diagnosed pathologically as a uterine choriocarcinoma. The patient was treated with 2 courses of MTX, but this regimen was not so effective. Because of persistent elevation of urinary hCG, 2 courses of etoposide were performed and hCG was rapidly reduced to within LH level. Etoposide (25 mg/day per os) was given to the patient for about three months since hospitalization and now complete remission has been obtained.
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Authors | J Kikuchi, T Sasaki, K Ishibashi, R Takaya, H Mori, H Endo, I Shima, T Moritsuka, K Takahashi |
Journal | Gan to kagaku ryoho. Cancer & chemotherapy
(Gan To Kagaku Ryoho)
Vol. 18
Issue 7
Pg. 1209-12
(Jun 1991)
ISSN: 0385-0684 [Print] Japan |
PMID | 2053779
(Publication Type: Case Reports, English Abstract, Journal Article)
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Chemical References |
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Topics |
- Administration, Oral
- Adult
- Choriocarcinoma
(drug therapy, surgery)
- Combined Modality Therapy
- Etoposide
(administration & dosage, therapeutic use)
- Female
- Humans
- Hysterectomy
- Remission Induction
- Uterine Neoplasms
(drug therapy, surgery)
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