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[A case of complete remission obtained with etoposide in uterine choriocarcinoma].

Abstract
A 27-year-old female was admitted to Sendai National Hospital complaining of continuous slight genital bleeding for about one and a half year after incomplete abortion. At first visit, urinary hCG was elevated to 32,000 IU/l and ultrasonography revealed a heterogeneous tumor in the uterus body. After abdominal simple total hysterectomy, the sample was diagnosed pathologically as a uterine choriocarcinoma. The patient was treated with 2 courses of MTX, but this regimen was not so effective. Because of persistent elevation of urinary hCG, 2 courses of etoposide were performed and hCG was rapidly reduced to within LH level. Etoposide (25 mg/day per os) was given to the patient for about three months since hospitalization and now complete remission has been obtained.
AuthorsJ Kikuchi, T Sasaki, K Ishibashi, R Takaya, H Mori, H Endo, I Shima, T Moritsuka, K Takahashi
JournalGan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 18 Issue 7 Pg. 1209-12 (Jun 1991) ISSN: 0385-0684 [Print] Japan
PMID2053779 (Publication Type: Case Reports, English Abstract, Journal Article)
Chemical References
  • Etoposide
Topics
  • Administration, Oral
  • Adult
  • Choriocarcinoma (drug therapy, surgery)
  • Combined Modality Therapy
  • Etoposide (administration & dosage, therapeutic use)
  • Female
  • Humans
  • Hysterectomy
  • Remission Induction
  • Uterine Neoplasms (drug therapy, surgery)

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